[M/O] Akkermansia muciniphila

0.

Akkermansia muciniphila 에대하여 조사해봤다. 

1. Akkermansia muciniphila 

장내 미생물군에 관한 논문을 읽으면서 이 종에 대해 알게 되었습니다. 이 종은 P9이라는 단백질을 생성하는데, 이 단백질이 L-Cell의 ICAM-2 수용체에 결합하여 (

일부 생체 내 연구(마우스)와 시험관 내 연구(인간 L-세포)에서는

)GLP-1의 분비를 촉진한다고 합니다. 

from Bio import Entrez
from Bio import SeqIO 
Entrez.email = "dhkscjsrudgh@gmail.com"
query = "Akkermansia muciniphila"
handle = Entrez.esearch(db = "nucleotide", term = query, retmax = 1) 
record = Entrez.read(handle) 
handle.close() 

print("유전체 ID 목록:", record["IdList"]) 

ids = ','.join(record["IdList"]) 
handle = Entrez.efetch(db = "nucleotide", id = ids, rettype = "gb", retmode = "xml")
genbank_data = Entrez.read(handle) 
handle.close() 
for entry in genbank_data:
    print(entry["GBSeq_locus"]) 
    print(entry["GBSeq_length"], "bp") 
    print(entry["GBSeq_strandedness"]) 
    print(entry["GBSeq_moltype"]) 
    print(entry['GBSeq_organism']) 

entry = genbank_data[0]
references = entry["GBSeq_references"] 
for reference in references: 
    ref_title = reference.get("GBReference_title", "No title") 
    print(ref_title)

 

 

output

유전체 ID 목록: ['2568469811']
NZ_JAUUSZ010000000
4675301 bp
double
DNA
Escherichia sp.
Metagenome assembled genome from liver transplanted non alcoholic fatty liver disease (NAFLD) patients stool samples and probable role of Akkermansia muciniphila in restoring liver health
Direct Submission

 

참고문헌 : A specific gut microbiota signature is associated with an enhanced GLP-1 and GLP-2 secretion and improved metabolic control in patients with type 2 diabetes after metabolic Roux-en-Y gastric bypass